North Carolina Central University
1801 Fayetteville St.
Durham, NC 27707
The causes of stroke, hypertension, diabetes and obesity are inter-related, impacted by a complex combination of genetic predisposition, physical and social environment, diet and lifestyle. The Cardio-Metabolic research program at BBRI uses collaborative, multi-disciplinary approaches to explore the roles of dietary calcium and stress on hypertension and obesity and the involvement of nuclear hormone receptors such as SXR (steroid and xenobiotic hormone receptor) in cardiovascular disease, obesity and alcoholic liver disease. Investigators use techniques in molecular and cell biology, biochemistry, animal husbandry, public health nursing and bioinformatics to explore the causes and effects of cardio-metabolic disease states, especially as these diseases impact individuals and communities of underserved minorities.