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Research Initiatives

In addition to training the world’s next great scientists, BRITE also provides its faculty with a world-class research facility that allows them to conduct studies spanning subjects such as:

  • High Throughput Screening
  • Liquid Handling and Automation
  • Assay Development
  • High-Content Analysis for lead optimization and biological relevance from screening data
  • Synthetic Organic Chemistry
  • Medicinal Chemistry, SAR
  • Protein Production, Proteomics
  • Molecular Biology, Plant Genetics
  • Biosensor Technology

Our industry-inspired core facilities allow us to truly connect education with real world practice – providing our students with the most comprehensive training possible and preparing them to step into jobs ready and able to make a difference on day one.

Here are just a few of the research initiatives currently being conducted at BRITE. Click on a faculty member to learn more about their specific projects.

Gordon Ibeanu, Ph.D.

  • Molecular mechanisms and cellular targets of novel agents in Alzheimer’s disease
  • G-protein coupled receptors as agents of human cancers.

Andy Li , M.D., Ph.D.

  • Mechanism and Treatment of Brain Damage After Cerebral Stroke and Traumatic Brain Injury
  • Exacerbation Effects of Hyperglycemia on Stroke and TBI
  • Mitochondrial Biogenesis as a Therapeutic Strategy for Neurodegenerative Disorders

Carla Oldham, Ph.D.

  • The Effects of Thyroid Hormone on the Differentiation of Neuronal Cells (collaboration with Dr. Dayami Lopez)
  • Drug repurposing for autoimmune diseases using A query based Approach (collaboration with Dr. Weifan Zheng)

John Scott, Ph.D.

  • Cancer Research
  • Chemical Biology

Jonathan Sexton, Ph.D.

  • Drug Discovery and Development for Type II Diabetes and Obesity
  • Quantitative Biology - High Content and High Throughput Assay Technologies
  • Multivariate Data Analysis and Exploratory Data Analysis for High-Content Imaging

Alfred Williams, Ph.D

  • Natural Products Synthesis
  • Drug Discovery
  • New Synthetic Methodologies

Kevin Williams, Ph.D.

  • Protein Modifications
  • Protein Stability and Formulation
  • Identifying Novel Cancer Therapeutics

Jiahua Xie, Ph.D.

  • N-Glycoengineering of tobacco plants to produce cytoprotective asialoerythropoietin (asialo-EPO) and therapeutic glycoproteins
  • Studying the functions of plant-produced therapeutic glycoproteins
  • Using variegated 'Pothos' (Epipremnum aureum) plants to study chloroplast biogenesis
  • Understanding the role of recycling methyl groups (one-carbon units) from alkaloids for plant primary metabolism and growth

Liju Yang, Ph.D.

  • Dieletrophoresis Enhanced Microchips for Bacterial Pathogen Detection
  • Nanomaterials Interfacing Biological Cells
  • Biosensors and Biochips for Early Cancer Diagnosis

Weifan Zheng, Ph.D.

  • Novel Computational Tools
  • Cheminformatics Approach to Model Neurodegenerative Disease Targets
  • Structure-Based Anesthetic Agent Discovery

Chiu-Yeuh Hung

  • Plant Biology

Qingping He

  • Histology
  • Cell Imaging 
  • High Throughput Screening 
  • Drug Discover

Syed Ahmad

  • Drug Discovery

Dayami Lopez, Ph.D.

  • Regulation of the Hepatic LDL Receptor and PCSK9
  • Role of Hypothyroidism on Alzheimer’s Disease
  • Role of Hypothyroidism on Breast Cancer

Rob Onyenwoke, Ph.D.

  • Mechanisms of Metabolic Diseases
 
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