Research

 

In addition to training the world’s next great scientists, BRITE also provides its faculty with a world-class research facility that allows them to conduct studies spanning subjects such as:

• High Throughput Screening
• Liquid Handling and Automation
• Assay Development
• High-Content Analysis for lead optimization and biological relevance from screening data
• Synthetic Organic Chemistry
• Medicinal Chemistry, SAR
• Protein Production, Proteomics
• Molecular Biology, Plant Genetics
• Biosensor Technology

Our industry-inspired core facilities allow us to truly connect education with real world practice – providing our students with the most comprehensive training possible and preparing them to step into jobs ready and able to make a difference on day one.

Here are just a few of the research initiatives currently being conducted at BRITE. Click on a faculty member to learn more about their specific projects.

Li-An Yeh, Ph.D.

• Neuroprotective Agents
• Role of Tau in Alzheimer’s Disease

Gordon Ibeanu, Ph.D.

• Neurodegenerative Diseases: Alzheimer’s Disease
• Neurodegenerative Diseases: Huntington Disease
• Role of G-protein Coupled Receptors in Oncogenesis

David Kroll, Ph.D.

• Pure Flavonolignans from Milk Thistle
• Discovery of Anticancer Natural Products

Andy Li , M.D., Ph.D.

• Mechanism and Treatment of Brain Damage After Stroke
• Exacerbation Effects of Diabetes and Hyperglycemia on Stroke

Carla Oldham, Ph.D.

• Investigation of the Role of CHK in Neuronal Development

John Scott, Ph.D.

• PON1 Transcriptional Regulation
• Regulation of PON1 Expression by Cytokines

Jonathan Sexton, Ph.D.

• Real Time Process Monitoring and Control
• Using Nanoparticle-Bio Conjugates to Increase Effective Dose Rates
• Treatments for Type-II Diabetes, Metabolic Syndrome and Cardiovascular Diseases

Alfred Williams, Ph.D

• Natural Products Synthesis
• Diversity Oriented Synthesis
• Drug Discovery

Kevin Williams, Ph.D.

• Protein Modifications
• Protein Stability and Formulation
• Identifying Novel Cancer Therapeutics

Jiahua Xie, Ph.D.

• Identification of Se-accumulating Genes in Se-hyperaccumulation Plants
• Novel Plant Expression Systems
• Genetic Cause of Defective Chloroplasts in Pale Yellow Sectors of Variegated Golden Pathos

Liju Yang, Ph.D.

• Dieletrophoresis Enhanced Microchips for Bacterial Pathogen Detection
• Nanomaterials Interfacing Biological Cells
• Biosensors and Biochips for Early Cancer Diagnosis

Weifan Zheng, Ph.D.

• Novel Computational Tools
• Cheminformatics Approach to Model Neurodegenerative Disease Targets
• Structure-Based Anesthetic Agent Discovery